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Molecules | Free Full-Text Mammalian DNA Kappa Activity Specificity
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Cryo-EM structure of human Pol κ bound to DNA mono-ubiquitylated PCNA | Nature Communications
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IJMS | Free Full-Text | Translesion Synthesis or Repair Specialized DNA Polymerases Limits Excessive Genomic Instability Replication Stress
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Translesion polymerase synthesis underlies replication | eLife
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kappa Inhibitors (IC50, Ki) | AAT Bioquest
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Translesion polymerase eta both facilitates DNA and promotes increased genetic variation at common fragile sites | PNAS
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Structural Basis for Human Polymerase Kappa Bypass Cisplatin Intrastrand Cross-Link as an Efficient and Accurate Extender - ScienceDirect
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Translesion polymerase synthesis underlies replication | eLife
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Phosphorylation Alters Properties of Pol η: Implications for Translesion - ScienceDirect
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DNA Polymerases as a Therapeutic Intervention against Cancer
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DNA Polymerases as a Therapeutic Intervention against Cancer
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Unravelling roles error-prone DNA polymerases in shaping cancer genomes | Oncogene
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| Free Full-Text of Genome Integrity: How Mammalian Cells Orchestrate Genome Duplication by Coordinating Replicative and Specialized DNA Polymerases
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kappa Inhibitors (IC50, Ki) | AAT Bioquest
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Inhibition host by virus ~ ViralZone
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Journal of Cellular Physiology | Cell Biology Journal Wiley Online
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Computer-aided identification, synthesis, and biological evaluation of DNA polymerase η inhibitors the treatment of cancer - ScienceDirect
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Translesion polymerase synthesis underlies replication | eLife
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Small-Molecule Inhibitor of Human DNA η the Effects of Cisplatin in Tumor Cells | Biochemistry
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Crystal of Catalytic Core of Human DNA Kappa: Structure
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Journal of Cellular Physiology | Cell Biology Journal Wiley Online
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Inhibition of Human DNA Polymerases Eta and by Indole-Derived Molecules Occurs through Distinct Mechanisms | ACS Chemical Biology
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Molecules | Free Full-Text Mammalian DNA Kappa Activity Specificity
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DNA eta protects human cells against DNA damage induced by the tumor temozolomide - ScienceDirect
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Frontiers | Early Drug Discovery Development Novel Cancer Therapeutics Targeting DNA Eta (POLH)